Mamoru Kanda Selected Research

pactimibe

8/2010

Novel acyl-CoA: cholesterol acyltransferase inhibitor: indoline-based sulfamide derivatives with low lipophilicity and protein binding ratio.

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Mamoru Kanda Research Topics

Disease

3	Atherosclerosis 08/2010 - 01/2004
3	Inflammation (Inflammations) 06/2006 - 09/2004
1	Body Weight (Weight, Body) 05/2018
1	Hepatocellular Carcinoma (Hepatoma) 05/2018
1	Obesity 05/2018
1	Hyperglycemia 06/2008
1	Necrosis 01/2008
1	Pleurisy (Pleuritis) 06/2006
1	Edema (Dropsy) 01/2006
1	Arthritis (Polyarthritis) 09/2004

Drug/Important Bio-Agent (IBA)

2	N- (4,6- dimethyl- 1- pentylindolin- 7- yl)- 2,2- dimethylpropanamideIBA 01/2008 - 01/2004
2	CholesterolIBA 01/2008 - 01/2004
2	Nitric Oxide Synthase (NO Synthase)IBA 06/2006 - 01/2006
2	NG-Nitroarginine Methyl Ester (L-NAME)IBA 06/2006 - 01/2006
2	Cyclooxygenase InhibitorsIBA 06/2006 - 01/2006
2	Indomethacin (Indometacin)FDA LinkGeneric 06/2006 - 01/2006
2	Nitroarginine (NG Nitro L Arginine)IBA 06/2006 - 01/2006
2	CarrageenanIBA 06/2006 - 01/2006
1	Pioglitazone (Actos)FDA Link 05/2018
1	KY-226IBA 05/2018
1	Glucose (Dextrose)FDA LinkGeneric 05/2018
1	Hemoglobins (Hemoglobin)IBA 05/2018
1	Insulin (Novolin)FDA Link 05/2018
1	Insulin ReceptorIBA 05/2018
1	Triglycerides (Triacylglycerol)IBA 05/2018
1	LeptinIBA 05/2018
1	Therapeutic UsesIBA 05/2018
1	Non-Receptor Type 1 Protein Tyrosine PhosphataseIBA 05/2018
1	pactimibeIBA 08/2010
1	1,2,3,4-tetrahydroisoquinolineIBA 08/2010
1	compound 21IBA 08/2010
1	PPAR gammaIBA 06/2008
1	acetyl-LDLIBA 01/2008
1	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 01/2006
1	NitratesIBA 09/2004
1	NitritesIBA 09/2004
1	ProstaglandinsIBA 09/2004
1	Collagen Type II (Type II Collagen)IBA 09/2004
1	Dinoprostone (PGE2)FDA Link 09/2004
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 09/2004
1	oxidized low density lipoproteinIBA 01/2004
1	LipidsIBA 01/2004

Therapy/Procedure

1	Oral Administration 05/2018
1	Therapeutics 06/2006